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Plasmapheresis (TPE)

Therapeutic plasma exchange (plasmapheresis)

Removing harmful substances from the blood plasma and replacing it, in a carefully monitored procedure.

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What is plasmapheresis?

Blood is drawn into an apheresis machine that separates the plasma (the liquid part of the blood) from the blood cells. The plasma, which can carry harmful antibodies or other substances, is removed. The blood cells are returned to you together with a replacement fluid.

Who may benefit

Therapeutic plasma exchange may be used for certain neurological, immune-mediated and transplant-related conditions, and for some blood conditions. Examples include Guillain-Barré syndrome, myasthenia gravis and thrombotic thrombocytopenic purpura (TTP). Your doctor will decide whether it is right for you.

What to expect

  1. 1

    Assessment

    A haematologist reviews your condition and tests.

  2. 2

    Access

    Our team prepares safe access to your blood, which may be through suitable veins or a central line.

  3. 3

    The exchange

    You rest comfortably while the machine works, and you are monitored throughout. Your team will tell you how long your session will take.

  4. 4

    After care

    You are observed and given clear follow-up instructions.

Frequently asked questions

You may feel the needle or line being placed. The exchange itself is usually comfortable and our team monitors you throughout.

It depends on your condition. Your doctor will advise.

Referrals from your doctor are welcome, but you can also contact us directly to discuss your situation.

Talk to us about plasmapheresis.